The Coulomb barrier, named after Coulomb's law, which is in turn named after physicist Charles-Augustin de Coulomb, is the energy barrier due to electrostatic interaction that two Atomic nucleus need to overcome so they can get close enough to undergo a nuclear reaction.
A positive value of U is due to a repulsive force, so interacting particles are at higher energy levels as they get closer. A negative potential energy indicates a bound state (due to an attractive force).
The Coulomb barrier increases with the (i.e. the number of protons) of the colliding nuclei:
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